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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX3X
All Species:
22.42
Human Site:
Y69
Identified Species:
35.24
UniProt:
O00571
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00571
NP_001347.3
662
73243
Y69
S
S
K
D
K
D
A
Y
S
S
F
G
S
R
S
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
D67
W
S
C
S
K
D
K
D
A
Y
N
S
F
G
S
Rhesus Macaque
Macaca mulatta
XP_001095294
910
100218
Y319
S
S
K
D
K
D
A
Y
S
S
F
G
S
R
S
Dog
Lupus familis
XP_861268
662
73195
Y69
S
S
K
D
K
D
A
Y
S
S
F
G
S
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62167
662
73083
Y69
S
S
K
D
K
D
A
Y
S
S
F
G
S
R
G
Rat
Rattus norvegicus
NP_001102328
659
72976
Y67
W
S
K
D
K
D
A
Y
S
S
F
G
S
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512924
651
71975
N63
Y
S
S
F
G
S
R
N
D
A
R
G
K
S
S
Chicken
Gallus gallus
NP_001025971
651
72031
Y67
T
S
R
D
K
D
A
Y
S
S
F
G
A
R
S
Frog
Xenopus laevis
P24346
697
77284
D110
W
N
S
G
R
D
K
D
A
Y
S
S
F
G
S
Zebra Danio
Brachydanio rerio
NP_571016
688
75828
G97
G
G
R
G
G
F
R
G
F
G
Y
D
N
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHP0
798
85063
Q184
S
G
S
N
L
N
E
Q
T
A
E
D
G
Q
A
Honey Bee
Apis mellifera
XP_391829
701
78642
A112
G
G
R
T
R
R
S
A
N
Q
E
N
G
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F9
646
69224
S63
G
G
Y
G
G
A
N
S
G
Y
G
G
R
G
Q
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
R58
V
T
G
G
D
F
F
R
R
A
G
R
Q
T
G
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
G83
G
N
W
P
A
P
G
G
P
P
G
P
G
F
E
Conservation
Percent
Protein Identity:
100
91.3
70.1
99.8
N.A.
98.6
95.3
N.A.
95.9
91.2
82.2
76.3
N.A.
51.7
58
N.A.
N.A.
Protein Similarity:
100
95.3
70.3
99.8
N.A.
99
97.1
N.A.
97.2
94.7
88
83.8
N.A.
63.4
70
N.A.
N.A.
P-Site Identity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
20
80
13.3
0
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
93.3
N.A.
26.6
100
33.3
26.6
N.A.
46.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.5
49.4
52
Protein Similarity:
N.A.
N.A.
N.A.
64.6
65.2
64.8
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
40
7
14
20
0
0
7
0
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
40
7
54
0
14
7
0
0
14
0
0
7
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
14
0
0
0
14
% E
% Phe:
0
0
0
7
0
14
7
0
7
0
40
0
14
7
0
% F
% Gly:
27
27
7
27
20
0
7
14
7
7
20
54
20
20
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
34
0
47
0
14
0
0
0
0
0
7
7
0
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
14
0
7
0
7
7
7
7
0
7
7
7
0
0
% N
% Pro:
0
0
0
7
0
7
0
0
7
7
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
7
0
0
7
7
7
% Q
% Arg:
0
0
20
0
14
7
14
7
7
0
7
7
7
47
0
% R
% Ser:
34
54
20
7
0
7
7
7
40
40
7
14
34
7
54
% S
% Thr:
7
7
0
7
0
0
0
0
7
0
0
0
0
7
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
20
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
40
0
20
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _